{"url":"https://newsforagent.com/news/2026-10-26/kreatis-japan-amicl-bd-cbi-2026","markdown_url":"https://newsforagent.com/news/2026-10-26/kreatis-japan-amicl-bd-cbi-2026.md","title":"Kreatis Japan Shows AMiCl-BD Biodegradability Module at CBI 2026","headline":"Kreatis Japan Presents AMiCl-BD Biodegradability Prediction Module at CBI Society 2026 Meeting","description":"Kreatis Japan presented a promotion poster for AMiCl-BD, a QSAR biodegradability module in its iSafeRat software, at the CBI Society 2026 meeting in Tokyo.","section":"Product Launches","published_at":"2026-10-26T09:33:42+00:00","modified_at":"2026-10-26T09:33:42+00:00","author":"News Desk","key_takeaways":["Kreatis Japan presented a promotion poster for AMiCl-BD at the CBI Society 2026 annual meeting at Tower Hall Funabori in Tokyo from October 26 to 29.","AMiCl-BD uses Random Forest and Support Vector Machine algorithms with MACCS Key fingerprint descriptors to predict readily-biodegradable or not readily-biodegradable classification.","Kreatis Japan was established in Tokyo in April 2026 as the first overseas subsidiary of the French-based company Kreatis."],"companies":[{"name":"Kreatis","is_primary":true,"profile_url":"https://akta.pro/company-profiles/02lmbnn/kreatis","website":"https://www.kreatis.eu"}],"source":{"publisher":"Prtimes","title":"KREATiS Japan株式会社、CBI学会2026年大会に参加","url":"https://prtimes.jp/main/html/rd/p/000000004.000183387.html"},"other_sources":[],"tags":["Product Launches","Kreatis"],"body_markdown":"[Kreatis](https://akta.pro/company-profiles/02lmbnn/kreatis) Japan presented a promotion poster for AMiCl-BD, a biodegradability prediction module within its iSafeRat QSAR software, at the CBI Society 2026 annual meeting at Tower Hall Funabori in Tokyo from October 26 to 29, according to [Prtimes](https://prtimes.jp/main/html/rd/p/000000004.000183387.html). The poster is at P04-15 in the first-floor exhibition hall.\n\n## AMiCl-BD Module and Its Prediction Methods\n\nAMiCl-BD, short for Aerobic Microbial Classification of BioDegradation, is a ready-biodegradability QSAR model compliant with the OECD's QSAR Assessment Framework. It is composed of two independent algorithms, Random Forest and Support Vector Machine. The module uses MACCS Key fingerprint as a descriptor to predict binary classification: readily-biodegradable or not readily-biodegradable. It also assesses the Applicability Domain and computes a reliability score called the Reliability Index of Prediction, or RIP.\n\nMany other biodegradability QSAR software do not allow users to customize the indices of prediction reliability, but in AMiCl-BD, users can choose MACCS Key or PubChem fingerprint for the calculation of similarity. New functionality will be implemented to find analogues from user-imported databases in the future. QMRF and QPRF are available. The promotion poster presents the predictivity performance of AMiCl-BD.\n\nThe promotion poster format, which started from this year's CBI meeting, differs from the ordinary poster presentation in that not only academic posters but also commercial posters such as product advertisements are admitted.\n\n## Kreatis Product and Partnership Record\n\nAccording to akta.pro [company records](https://akta.pro/company-data), Kreatis released the MechoA+ profiler in April 2026 as a free add-in to the OECD QSAR Toolbox, featuring 152 structural alerts covering about 80% of more than 70,000 substances, in collaboration with Liverpool John Moores University. The same records list a partnership with the OECD, with the MechoA+ profiler now available as a free add-in to the OECD QSAR Toolbox, recognition from the OECD for the MechoA profiler being included in the official Toolbox, and collaboration with ECHA on Toolbox development. Kreatis also updated the CLASS skin sensitisation model in September 2024 to meet QSAR Assessment Framework requirements and presented it at EUROTOX2024, and announced iSafeRat Desktop v4.3 and the SafePAC application in July 2024.\n\n## Kreatis Japan's Tokyo Establishment\n\nKreatis Japan was established in Tokyo in April 2026 as the first overseas subsidiary of the French-based company Kreatis. In addition to selling iSafeRat licenses, Kreatis provides support on QPRF, the QSAR Prediction Reporting Format, and training on in silico tools, according to its website.\n","publisher":{"name":"News for Agent","url":"https://newsforagent.com"}}